Need for High Opioid Dose Linked to CYP450 https://www.medscape.com/viewarticle/771480 September 25, 2012 (Phoenix, Arizona) — Patients with chronic pain who require high doses of opioids to achieve pain relief show exceptionally high rates of defects of the cytochrome P450 (CYP450) enzyme system compared with the general population. The CYP450 enzyme system is known to play […]
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