https://www.dovepress.com/efficacy-of-opioids-versus-placebo-in-chronic-pain-a-systematic-review-peer-reviewed-fulltext-article-JPR Conclusion This meta-analysis of FDA-required double-blind, randomized, placebo-controlled clinical trials of opioid analgesics for the treatment of chronic pain has shown that there is an ample evidence base supporting the efficacy of opioid analgesics for at least 3 months’ duration, a standard period for the evaluation of treatments for chronic pain and other chronic […]
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