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https://www.pharmaciststeve.com/harmful-effects-of-untreated-pain/

Here is four quotes from the CDC opiates guidelines:

https://www.cdc.gov/mmwr/volumes/65/rr/rr6501e1.htm

“The guideline is intended to ensure that clinicians and patients consider safer and more effective treatment, improve patient outcomes such as reduced pain and improved function.”

“Clinicians should consider the circumstances and unique needs of each patient when providing care.”

“Clinical decision making should be based on a relationship between the clinician and patient, and an understanding of the patient’s clinical situation, functioning, and life context.”

“This guideline provides recommendations for primary care clinicians who are prescribing opioids for chronic pain outside of active cancer treatment, palliative care, and end-of-life care.”

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Here is four quotes from the CDC opiates guidelines:

https://www.cdc.gov/mmwr/volumes/65/rr/rr6501e1.htm

“The guideline is intended to ensure that clinicians and patients consider safer and more effective treatment, improve patient outcomes such as reduced pain and improved function.”

“Clinicians should consider the circumstances and unique needs of each patient when providing care.”

“Clinical decision making should be based on a relationship between the clinician and patient, and an understanding of the patient’s clinical situation, functioning, and life context.”

“This guideline provides recommendations for primary care clinicians who are prescribing opioids for chronic pain outside of active cancer treatment, palliative care, and end-of-life care.”

https://globalrph.com/medcalcs/opioid-pain-management-converter-advanced/

Please review these important points:

1. 1. Published equianalgesic ratios are considered crude estimates at best and therefore it is imperative that careful consideration is given to individualizing the dose of the selected opioid. Dosage titration of the new opioid should be completed slowly and with frequent monitoring.
   2. Conversion ratios in many equianalgesic dosing tables do not apply to repeated doses of opioids.
   3. The amount of residual drug in the patient’s system must be accounted for. Example: fentanyl will continue to be released from the skin 12 to 36 hours after removal of the patch. Residual effects from discontinued long-acting formulations should also be assessed before converting a patient to a new opioid.
   4. Review the concept of incomplete cross-tolerance:

1. The use of high but ineffective doses of a previous opioid may result in overestimation of the converted opioid.
2. Ideally, methadone conversions (especially patients who were previously receiving high doses of an opioid) should only be attempted in cooperation with a pain specialist or a specialist in palliative medicine.

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call the Supreme Court to share your public opinion of the mandates and freedom, ahead of the hearing on Friday.
Call one of these Supreme Court of the United States phone numbers to leave your message: Clerk’s Office: 202-479-3011 or Public Information Office: 202-479-3211
Choose to leave ONE of these messages (or make your own brief message) with the Supreme Court:

Message 1: I would like the Court Justices to know, with the utmost of respect, that I am concerned about the infringement of Americans’ Constitutional freedom that imposing vaccine mandates presents. Please let them know that Americans desire our guaranteed freedom.

Message 2: On Friday, the Justices will be hearing about the vaccine mandates. I wish to respectfully register my concern about the infringement of personal and religious freedom that these mandated medical treatments have trampled on.

Message 3: Please relay to the Justices that I am praying for each one of them by name as they hear a critical religious freedom, medical freedom and personal freedom case of the vaccine mandates.

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Another Variant – This Time With a Self-Aggrandizing Name

https://www.acsh.org/news/2022/01/06/another-variant-time-self-aggrandizing-name-16044

Original photo: Wikimedia Commons

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In 1992, Jim Gray, a conservative judge in conservative Orange County, California, held a press conference during which he recommended that we rethink our drug laws. Back then, it took a great deal of courage to suggest that the war on drugs was a failed policy. Today, more and more Americans are coming to the realization that prohibition’s costs—whether measured in lives and liberties lost or dollars wasted—far exceed any possible or claimed benefits. Reason.tv’s Paul Feine interviewed Gray about drug policy and the prospects for reform. The interview was shot by Alex Manning and edited by Hawk Jensen. Judge Jim Gray is the author of Why Our Drug Laws Have Failed and What We Can Do About It: A Judicial Indictment of the War on Drugs.

Could all this “dust up” over mandatory vaccinations, mandating mask wearing… no testing for antibodies to determine “natural immunity ” .. failure of the current administration to order adequate supplies of various “stuff” deemed necessary to stop the spread of the COVID-19 virus – which has mostly failed miserably…  the lack of monoclonal antibodies … because they were not ordered by the current administration.

Could all this bring into focus what legal right the federal/state bureaucracies have to force citizens to take certain vaccinations and/or prohibit people from taking certain categories of medications approved by our FDA – as being safe for human use.  Could this COVID-19 pandemic potentially force the change of the Federal/State bureaucracies’ policies on all drug use and/or abuse.  After all the two drugs that contribute to the deaths of abt 550,000/yr of US citizens is Alcohol & Nicotine… are PERFECTLY LEGAL SUBSTANCES/DRUGS…. they are not MEDICATIONS… there is a difference between a medication and a drug.

That is abt 7-8 times the people killed in 2021 by the use/abuse of illegal controlled substances… which everyone is screaming from the roof tops about.  When did some deaths become socially acceptable and others are demonized…  could the big difference be the healthy tax revenue stream that goes to the Feds & states… that comes from those two legal drugs – Alcohol & Nicotine ?

could the CONVERSATION BE CHANGING ?

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The United States accounts for five percent of the world’s population but consumes almost 70 percent of the total global opioid supply, creating an epidemic that has resulted in tens of thousands of deaths each year. How did we get here, and what can we do about it? In this personal talk, Travis Rieder recounts the painful, often-hidden struggle of opioid withdrawal and reveals how doctors who are quick to prescribe (and overprescribe) opioids aren’t equipped with the tools to eventually get people off the meds. Check out more TED Talks: http://www.ted.com The TED Talks channel features the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on

Technology, Entertainment and Design — plus science, business, global issues, the arts and more.

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Critics question Biden FDA’s approval of COVID boosters for children: ‘Slap in the face to science’

https://www.foxbusiness.com/lifestyle/joe-biden-backlash-fda-process-booster-shots-children

One health expert says it’s ‘unconscionable’ that the FDA’s advisory panel is not being consulted on boosters

President Biden is yet again facing backlash over the FDA’s booster approval process, which recommended boosters for children this week without convening a panel of advisors to weigh in on the matter. 

“Dear President Biden, FDA is bypassing it’s scientific advisors to authorize boosters for all kids 12-15 next week. This is unconscionable – undermines the integrity of the FDA’s standard process! Please require FDA to put this authoriz [sic] before the VRBPAC advisory comm for a vote!” Dr. Marty Makary, chief of the Johns Hopkins Islet Transplant Center and Fox News contributor, tweeted Saturday. 

The Vaccine and Related Biological Products Advisory Committee voted against giving the Pfizer-BioNTech’s COVID-19 booster shots to most people back in September. It instead voted to limit boosters to those aged 65 and older, as well as to people at risk of severe illness, citing the lack of evidence showing the boosters are safe for younger people.  

“We’re being asked to approve this as a three-dose vaccine for people 16 years of age and older, without any clear evidence if the third dose for a younger person when compared to an elderly person is of value,” committee member Dr. Paul Offit, director of the Vaccine Education Center at Children’s Hospital of Philadelphia, said at the time. 

The controversy over boosters in the early fall was compounded when two FDA officials – the director of the FDA’s Office of Vaccines Research & Review, Marion Gruber, and its deputy director Phil Krause – resigned from the agency.

The pair issued a scathing criticism of the widespread use of boosters in a piece published in the Lancet on Sept. 13, which was co-authored by a handful of experts warning that “current evidence does not appear to show a need for boosting in the general population, in which efficacy against severe disease remains high.”

By November, however, the FDA approved the Pfizer-BioNTech and Moderna vaccine boosters for everyone 18 and older without input from the advisory committee. 

The agency said at the time that it did not convene its advisory panel because the committee had already discussed the use of boosters and “the requests do not raise questions that would benefit from additional discussion,” the New York Times reported on Nov. 19. 

The FDA approved the Pfizer-BioNTech COVID-19 vaccine booster for 16 and 17-year-olds last month, and broadened eligibility Monday to 12-15 year olds. 

Former FDA commissioner during the Trump administration, Scott Gottlieb, said during an appearance on “Face the Nation” Sunday that schools should not mandate boosters for children, noting that the durability of vaccines in 12 to 16-year-olds “has been more robust than what we’ve seen in adults.” He added that kids overall are “at less risk overall from the infection.”

Dr. Makary agrees.  

“It is a slap in the face to science for @US_FDA to circumvent the standard convening of the expert advisory board… FDA is quietly doing this because their experts previously voted it down, voicing concerns about medical harms,” Makary tweeted Saturday. 

Makary added in comment to Fox News on Monday that it’s within Biden’s “jurisdiction to demand that his FDA put the decision to a vote by the experts as was done with other major FDA [Emergency Use Authorizations].”

Dr. Marc Siegel, professor of Medicine at the NYU Langone Medical Center and Fox News contributor, said he supports the advisory board taking up the issue because they need to “figure out the utility of it.”

“I don’t want anybody to be suggesting this vaccine, or its boosters, are unsafe for that group. That’s wrong. And the purpose of convening the advisory committee is not to question safety. It’s to question who should get it,” Siegel told Fox Digital on Monday. 

“If we start suggesting that this, this vaccine is unsafe, then we’re playing into the hands of the anti-vaxers, who are filling hospitals.”

The New York Times reported on Dec. 30 that some experts said that the Biden administration’s focus on getting younger people boosters is misguided and officials should instead work on vaccinating those who have not yet gotten the shots. Offit told the outlet that getting such shots to young Americans was “focusing on the people who are already protected.”

Republican Sen. Rand Paul, who is also a physician, criticized the Biden administration on Twitter Sunday for the government “ignoring its own rules to push booster vaccines on kids for a disease is that is less deadly in children than the seasonal flu.”

Makary argued in a Wall Street Journal op-ed published last month that booster mandates for young people “will cause medical harm for the sake of transient reductions in mild and asymptomatic infections.” He cited a December study by Oxford researchers that found “young people suffered myocarditis, pericarditis and arrhythmias more frequently from Moderna’s vaccine than from Covid itself.”

While the long-term cardiac effects of boosters in younger people is “unknown.”

“Forcing immune, young, healthy, low-risk students to get a third vaccine shot is excessive and wasteful. These precious vaccine doses should be going to poor countries that still don’t have enough,” Makary concluded in his op-ed. 

The White House referred Fox News to the FDA when approached for comment on the concerns from health officials. 

The FDA directed Fox News later Monday to a press call where the director of the Center for Biologics Evaluation and Research within the FDA said the advisory board is called upon at the discretion of FDA officials. 

“The reason for not taking it to our advisory group: We use our discretion when we bring things to advisory group. When we feel like there is some question that is likely to actually need public discussion,” Dr. Peter Marks said on the call. “We sometimes consult our advisory committee chairs to decide what questions to bring to committee.”  

He explained that the increase in cases in the last 48 hours prompted officials “to try to move as quickly as we possibly could.” 

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