US DEA Says They Shut Down “Dark Net” Market for Heroin, Fentanyl

www.nwigazette.com/2017/07/20/us-dea-says-they-shut-down-dark-net-market-for-heroin-fentanyl/

“This is likely one of the most important criminal investigations of the year taking down the largest dark net marketplace in history”, said Attorney General Jeff Sessions. Guns, drugs and illegal documents allegedly traded on “dark net” site Alphabay

July 20, 2017-The United States Drug Enforcement Administration announced today that they shut down a “dark net site” which they allege was linked to the illegal sale of heroin and fentanyl. “The Justice Department today announced the seizure of the largest criminal marketplace on the Internet, AlphaBay, which operated for over two years on the dark web and was used to sell deadly illegal drugs, stolen and fraudulent identification documents and access devices, counterfeit goods, malware and other computer hacking tools, firearms, and toxic chemicals throughout the world” the agency announced.

The massive international criminal investigation was led by law enforcement officials from the United States and included authorities in Thailand, the Netherlands, Lithuania, Canada, the United Kingdom, and France, as
well as the European law enforcement agency Europol. “On July 5, Alexandre Cazes aka Alpha02 and Admin, 25, a Canadian citizen residing in Thailand, was arrested by Thai authorities on behalf of the United States for his role as the creator and administrator of AlphaBay. On July 12, Cazes apparently took his own life while in custody in Thailand. Cazes was charged in an indictment (1:17-CR-00144-LJO), filed in the Eastern District of California on June 1, with one count of conspiracy to engage in racketeering, one count of conspiracy to distribute narcotics, six counts of distribution of narcotics, one count of conspiracy to commit identity theft, four counts of unlawful transfer of false identification documents, one count of conspiracy to commit access device fraud, one count of trafficking in device making equipment, and one count of money laundering conspiracy. Law enforcement authorities in the United States worked with numerous foreign partners to freeze and preserve millions of dollars worth of cryptocurrencies that were the subject of forfeiture counts in the indictment, and that represent the proceeds of the AlphaBay organizations illegal activities” officials stated.

“On July 19, the U.S. Attorneys Office for the Eastern District of California filed a civil forfeiture complaint against Alexandre Cazes and his wife’s assets located throughout the world, including in Thailand, Cyprus, Lichtenstein, and Antigua & Barbuda. Cazes and his wife amassed numerous high value assets, including luxury
vehicles, residences and a hotel in Thailand. Cazes also possessed millions of dollars in cryptocurrency, which has been seized by the FBI and the Drug Enforcement Administration (DEA)” the statement continues. Legitimate cryptocurrency trading can be done with the help of brokers such as IronFX, and  IronFX complaints section gives an idea of its functions.

This is likely one of the most important criminal investigations of the year taking down the largest dark net marketplace in history, said Attorney General Jeff Sessions. DEA alleges that Alphabay boasted over 40,000 active sellers and 200,000 users. “Around the time of takedown, there were over 250,000 listings for illegal drugs and toxic chemicals on AlphaBay, and over 100,000 listings for stolen and fraudulent identification documents and access devices, counterfeit goods, malware and other computer hacking tools, firearms and fraudulent services.”

Officials say the investigation is related to numerous pending prosecutions in the United States and investigation is ongoing. Charges contained in an indictment or complaint are merely allegations, and the defendant is presumed innocent unless and until proven guilty beyond a reasonable doubt in a court of law.

Filed under: General Problems | 3 Comments »

Trump administration wants to rollback controversial civil forfeiture limits

http://www.wtsp.com/news/politics/trump-administration-wants-to-rollback-controversial-civil-forfeiture-laws/457901213

U.S. Attorney General Jeff Sessions said this week that the new administration plans on increasing the use of civil asset forfeiture, a controversial technique that allows police to seize cars, cash, and other property from individuals, even if they weren’t charged with a crime.

10Investigates was one of many news outlets to expose civil forfeiture abuses in recent years, and in 2015, the Obama administration drew praise from many Democrats and Republicans after it tightened some of the federal rules on seizures, aiming to limit abuses.

In the last decade alone, the Drug Enforcement Administration (DEA) reports seizing more than $3 billion from individuals who were not charged with crimes.

But Sessions said by increasing the amount of property seized, the government could better-target drug traffickers.

That drew sharp criticisms from the Institute for Justice Director, whose senior attorney, Darpana Sheth, said in a statement, “Civil forfeiture is inherently abusive. No one should lose his or her property without being first convicted of a crime, let alone charged with one. The only safeguard to protect Americans from civil forfeiture is to eliminate its use altogether. The Department of Justice’s supposed safeguards amount to little more than window dressing of an otherwise outrageous abuse of power.

“We have consistently warned that the modest reforms put in place in 2015 could be rolled back with the stroke of a pen—and that is precisely what Attorney General Sessions has done today. The DOJ’s directive, announced to a room full of law enforcement officials who stand to reap the profits of this new policy, shows the fundamental absurdity of a system of justice which prioritizes funding law enforcement over protecting constitutional rights or fighting crime.”

Following 10Investigates’ civil forfeiture stories in 2015, Florida joined 23 other states in passing recent reforms on the issue.  Florida law now requires a conviction for law enforcement agencies to permanently keep your property, but loosening the federal restrictions could open a new window for Florida law enforcement agencies to seize assets under federal law.

Find 10Investigates’ Noah Pransky on Facebook or follow his updates on Twitter. Send your story tips confidentially to npransky@wtsp.com.

Filed under: General Problems | 4 Comments »

New Opioid Guidelines Redefining ‘Compassion’ For Montana Doctors

http://mtpr.org/post/new-opioid-guidelines-redefining-compassion-montana-doctors

As the nation faces an epidemic of opioid drug abuse after a decade of aggressively prescribing narcotics , Montana doctors are becoming more cautious about giving painkillers to chronic pain patients.

It’s changing some patients ability to get treatment and what is considered compassionate care for chronic pain.

Last spring, the federal Centers for Disease Control and Prevention issued new opioid prescribing guidelines for doctors, designed to address the national epidemic.

In response, Butte Doctor Shawna Yates, the Medical Director of Southwest Montana Community Health Center, sent a letter to pain patients saying the clinic would no longer prescribe high doses of opioid painkillers.

“For me, personally, I really do try to stress that I believe in their pain,” Yates says, “that I understand where the concern that they’re having is coming from.”

But Yates says, her clinic’s new policies for the highly addictive drugs have caused a lot of patients to seek care elsewhere.

“I’ve said it more often in the last six months than ever before. I’m not leaving them. If they decide to leave, they’re leaving me.”

The CDC guidelines encourage primary care doctors to become less dependent on opioid medications for treating chronic pain because of the drugs’ serious side effects, including addiction.

The Butte clinic started tightening its prescribing policies back when it had about 700 pain patients coming in for treatment, years before the CDC released its guidelines.

It did things the CDC guidelines would eventually call for, like random drug tests, to make sure patients weren’t abusing their medication, or taking additional drugs. The clinic also required patients to only fill their prescriptions at one pharmacy.

“And many of those patients left” Yates’ clinic, she says. “There are many patients that aren’t willing to follow those recommendations.”

After the clinic put in the additional rules for pain treatment, and sent out a letter telling patients the clinic was adopting the federal guidelines, implementing a cap on how many pills it prescribed, about 400 patients left the clinic.

Doctor Andrew Kolodny, with the national advocacy group Physicians for Responsible Opioid Prescribing, says lowering the limit on prescription painkillers is a good policy and it’ll help patients who are harmed by high doses.

“For patients who are being required to taper down who are on high doses, that’s appropriate,” Kolodny says.

Kolodny is also the co-director of the opioids policy research collaborative at Brandeis University in Boston.

“As Doctors start to figure out that we shouldn’t have been prescribing in this way, these patients are at risk of being cut off from a legal supply of opioids,” Kolodny says. “And that’s why we really do need a compassionate response for that population.”

Kolodny says the problem isn’t people using opioids because it makes them feel good, snagging a few pills to get a quick high. The issue, he says, is the millions of Americans who were legally supplied, and hooked, on these drugs during an era of medicine where opioids were believed to be a good option to treat pain.

Now, Kolodny says the most compassionate thing doctors can do is slowly, and safely, begin to take away the painkillers and start treating these patients for narcotic addiction. Because he, and some doctors around Montana, say regular use of opioids can actually make pain worse.

But pain patients like Dalaine Propp don’t like being told they drug abusers.

“We either do what they say we do or we get kicked to the curb,” Propp says.

Propp is a member a pain patient support group in Great Falls. They got together because they feel they’re being treated unfairly. There’s about 100 members in the group’s Facebook page, and this spring, a couple dozen people showed up to the group’s first meeting.

Propp says she’s tried alternatives to opioids.

“I did the physical therapy, we looked at the surgery option, we’ve done injections, and unfortunately the only thing that has kept me working and kept me going was the opiate medication,” she says. “I think this whole thing with the CDC has scared even regular practitioners to even start people on any kind of pain regime.”

“I have no doubt that there are patients who are telling you that they feel agonizing pain,” Kolodny says,”and then they take their opioid and they’re able to get out of bed and function and brush their teeth and have some type of life, and that without the opioid they wouldn’t be able to get out of bed and they’d feel like they want to commit suicide.

“I can tell you that’s exactly how people who are heroin users who are opiate addicted feel until you use your first dose of heroin in the morning you’re feeling agonizing pain and discomfort,” he says.

Kolodny says too few doctors who prescribe opioids also prescribe drugs that can help patients wean off the painkillers. If doctors want to help chronic pain patients move past opioids, he says, more doctors need that addiction medication training.

There are patients who say that once they got off opioids, it became easier to deal with their underlying pain issue, some describe it like a fog being cleared.

At the clinic where Doctor Shawna Yates works, in Butte, patients are required to go to mental health specialists and encouraged to keep up a good diet and get enough sleep.

“I think the biggest thing we need to do moving forward as a culture is find better ways to treat pain,” Yates says.

“The hardest part is to know that there are people out there that are not getting good pain relief, and with a culture that is getting older and that are suffering, that’s the part that bothers me,” she says. “We can take stuff away, and we can know that there is harm related to this. I don’t think the biggest challenge is taking these away. I think the biggest challenge is finding out what we are going to do in place of it.”

Yates says as she, and other doctors learn more about how to treat pain, she wants patients to know she’s not abandoning their care, even if that’s exactly how some patients see it.

Filed under: General Problems | 4 Comments »

Dr. Andrew Kolodny has issued an epic challenge to the pain patient community. He wants to know — “Outside of palliative care, dangerously high doses should be reduced even if patient refuses. Where exactly is this done in a risky way?” and, “I’m asking you to point to a specific clinic or health system that is forcing tapers in a risky fashion.” Of course, pain patients must respond. If you have been forced to taper and you have been harmed by a specific doctor or clinic, please issue a tweet in reply to Dr. Kolodny @andrewkolodny. If you don’t have a twitter account, now is a good time to get one. Don’t be shy. Don’t hold back. Tell it like you have experienced it in 140 characters. COPY, PASTE, SHARE.

Filed under: General Problems | 7 Comments »

WV Board of Pharmacy dismisses director

http://www.wvgazettemail.com/news-health/20170718/wv-board-of-pharmacy-dismisses-director

The West Virginia Board of Pharmacy has dismissed its executive director amid a review of rules that require drug distributors to report on pharmacies that order a “suspicious” number of painkillers and other powerful prescription medications.

David Potters, who also was the pharmacy board’s general counsel, departed after 10 years with the agency.

Asked for the reason for Potters’ dismissal, board Chairman Dennis Lewis said, “I’m not at liberty to discuss that. You just don’t do that.”

The board has appointed Mike Goff, an agency administrator and former West Virginia State Police trooper, as acting executive director. Goff oversees the state’s prescription monitoring database. The board plans to advertise for a new general counsel to handle legal matters.

Earlier this year, the pharmacy board hired a chief financial officer for the first time — a move designed to lessen Potters’ workload. The board dismissed Potters during an emergency meeting late last month. He declined to comment Tuesday.

In December, a Gazette-Mail investigation found that the pharmacy board failed to enforce rules to report suspicious orders for controlled substances in West Virginia. Potters acknowledged that the rules, which were adopted years before he was hired, weren’t on the agency’s radar.

Those same years, the pharmacy board was giving spotless inspection reviews to small-town pharmacies that ordered more pills than could be possibly taken by people who really needed medicine for pain, the newspaper found.

In response, the board has spent the past six months developing a reporting system to flag suspect drug orders.

Drug wholesale distributors — companies that ship drugs from manufacturers to pharmacies — are cooperating with the review, Lewis said.

The board is developing a standard form for drug distributors to report suspicious orders from pharmacies for painkillers and anti-anxiety medications, Lewis said. The reporting system is designed to curb the proliferation of controlled substances.

Drug distributors must submit the reports monthly, according to the board’s proposed rules.

“We’ll use the reports to make an evaluation of what is really going on,” Lewis said. “We want something that is readable and usable.”

The proposed changes also will require wholesalers to disclose whether they have had any questionable drug orders from pharmacies.

“We’re wanting them to do ‘zero’ reporting if they don’t have any suspicious orders, or if they do have them, we want them,” Lewis said. “And we want to be able to pin down what the suspicious order is for.”

Also, the board plans to require wholesalers to report when they refuse to ship controlled substances to specific pharmacies.

“If they’re going to cut off a pharmacy, we want to know about it,” Lewis said.

The pharmacy board is expected to discuss the proposed rules to track suspicious drug orders at a meeting next week.

Reach Eric Eyre at ericeyre@wvgazettemail.com, 304-348-4869 or follow @ericeyre on Twitter.

Isn’t it a number of different city, county, state agencies that are contemplating suing just about anyone and everyone in the prescription distribution system… accusing them of being the cause of the “opiate epidemic” in WV ?

I think that it was  William Shakespeare in the 1600 play Hamlet that stated  “The lady doth protest too much, methinks ”

Perhaps those in WV… should first clean up their own house before they start suing others for their problems ?

Filed under: General Problems | 2 Comments »

I read your article several times and I am really upset over what transpired tonight at CVS when trying to fill my script for OxyContin 80mg. I take it 3x a day as the time released med and Oxycodone 30 mg for short acting  medicine for my chronic pain too many diagnosis to list. Been a chronic care patient for 13 years. Never had a problem until recently.

I switched from my mail order to going to my local pharmacies as it was getting expensive trying to pay for ups overnight.

It Seems that this female CVS pharmacist who gladly filled my scripts last month and said it would not be a problem now tells me she thinks I am taking too many pills and refused to fill my scripts.

I was just in an auto accident and fractured my wrist, along with many other injuries. I Was in severe pain and on my last day of pills. She said she thought my Dr was overprescribing and wanted to talk to him. Well he was out of the country getting married and would not be back for two weeks so she let me go and did not give two shits that I was going to be without my meds. In pain and going through withdrawals. I don’t know what to do.

I drive to 30 different pharmacies. All walgreens and cvs pharmacies and they all said they did not have my medicine. I know that’s a lie!!!

30 stores and not one had even one of my scripts?

I am now in severe pain. I am ready to go to the ER but I need my scripts filled.

If my Dr can’t talk to anyone for two weeks what am I supposed to do?

What action can I take against this pharmacist who made her own decision like she is my Dr and question my Drs valid script? Pain meds I have been on for years. I never had this happen before.

Help. 

Filed under: General Problems | 1 Comment »

I am a 60 yr old female from ME, I have had a sleep disorder that is genetically related my paternal side with my g-mother, my dad, his 2 sisters and sadly i passed it to our son who i see going thru struggles in treatment but he is not as severe as i am. i was able to control it in my teens by taking a daily nap but around my 30’s it seemed to change overnite with sleep episodes while driving ,while standing eating etcc and this caused multiple auto accidents and falls with fractures and the impact on my marriage by not being able to go places with my husband, surprisingly we are still together, but my children beared the worse like always watching me if my head started to nod at the wheel and they would yell and shake me, and i am embarrassed to tell you that during those cold snowy ME winters my kids waited for me to pick them up as thay had to stay over for some activity, i was suppose to be there at 3pm but after work i layed downed set alarm and never woke til 6pm never hearing the phone ring and here thye were out in the cold. 

But what floors me my doctors knew all that was gaing on and my 10 MSLT/PSG sleep studies that i was put thru all showed the same results sleep latency 0.5-1 min to sleep but no REM onset. the positive HLA test thye said meant nothing. i was told “BE CAREFUL DRIVING” Thye refused me stimulants for fear addiction, i had been contacting Stanford University Narcolepsy research on my untreated disease and the fears my docotrs had even though these specialist claimed and boosted how they were the only ME expert  in Narcolepsy?? 

Well when i told the doctor that Dr Mignot from Stanford would speak with my doctors to lessen there fear and to educate them about the research and how important it is to treat the symptoms asap , he also stated that  many doctors are unaware that each patient has to be treated individual to lessen the symptoms and for safety to avoid accidents and that the PDR was not appropriate as many need much higher doses and that addiction was not evident in Narcolepsy research. My doctor flatly refused as did 2 others and they were not happy with my suggestion of working with Dr Mignot, they took it as a insult so i was never followed up and a letter by one wrote derogatory remarks about my personality and that all Narcoleptics were “hard to deal with as they have psych issues” I was so angery . I was a RN and loved my career and caring for patients but i can not advocate for myself. i finally was treated when i went to live in AZ by a Indian doctor that was familar with this disease, he put me on Desoxyn up to 60 mg day and i could not believe i had a life again, but upon return to Maine i was not given this med and sent to a shrink who gave me Dexedrine 40 mg and whjile on that i got into another accident rearending a car as the doctor made me drive 1 hour away knowing my driving history. Know i am dealing with chronic pain have MGUS, urine protein 498, IgG low and Kappa/Lambda FLC and Kappa FLC high with beta fraction abnormal , i have widespread livedo vasculopathy or livedo as it was diagnosed “google search” my face also get pasty white which my family states i look like dead person walking, i am bedridden practically and also hgad a fully detached ball socket R shoulder that was missed in ME and found in Fl 1st viisit , had surgery 4 disposible rods placed in 2013 and rods still there , had mri which showed severe Chrondomalacia with raggeity bicep but my surgeon refuses surgery asked why he said your wife shoulder was detached for too long and the damage was severe and she must of been in severe pain, i also had a Catacholamine attck and was kept overnight . the opiods i am on help but ties i could use more and my pain doctor says i can do no more for you. i am on Percocet 10/325 4 day and Morphine ER 3 day. poor quality life not dependable to go places as i get to much pain and ask to leave, i do not eat much and i would rather die than live like i am as i have no joy even my children i dread to come visit as i am bed , it takes everything out of me to sit up and viisit, i am catholic so suicide is not a optiion for me, i have asked Pallaitive care but get a deer in headlite and told i am too young. in ME i had to fly back alone to FL as Govener made patients like me unable to get meds. what do u suggest. i am on ssdi medicare

Filed under: General Problems | Leave a Comment »

Family sues UCSF for agreeing, then refusing to help woman die

http://www.mercurynews.com/2017/07/17/family-sues-ucsf-for-agreeing-then-refusing-to-help-woman-die/

In what may be the first-of-its-kind lawsuit related to California’s End of Life Option Act, the family of a San Francisco terminally ill cancer patient is suing the UC San Francisco Medical Center alleging that her physician and the system misrepresented that they would help the dying woman use California’s right-to-die law when her time came.

Instead, according to the July 7 civil lawsuit filed in San Francisco Superior Court, Judy Dale’s wish for a peaceful death through the state’s new aid-in-dying law was denied to her by the defendants’ “conscious choice to suppress and conceal’’ their decision that they would not participate in the law, despite her repeated requests to doctors and social workers throughout last summer that she intended to have a peaceful death via aid-in-dying. The suit also names the university’s Helen Diller Family Comprehensive Cancer Center, UCSF Health, a UCSF oncologist and the UC Board of Regents.

UCSF declined Monday to comment on the matter.

The 17-page lawsuit alleges that Dale “repeatedly requested” the reassurance of UCSF doctors and social workers that they would participate in the end of life law, “which they gave her over and over.’’ On Aug. 18, the suit says, Dale “was shocked to learn from her UCSF social worker’’ that her doctors had decided to deny any eligible patient who requested aid in dying, “notwithstanding their many prior representations that they would provide it.’’

After caring for the 78-year-old Dale as an inpatient throughout the summer of 2016, UCSF discharged Dale to her home to die without their assistance, the lawsuit says.

That set in motion “an urgent, panic-filled search for a physician who would be willing’’ to help her fulfill the process required by the End of Life Option Act, and obtain a prescription for the lethal medication in time to use it.

According to the lawsuit, Dale’s frenzied search occurred even though UCSF’s website says, “if you doctor does not feel comfortable using the act, your social worker will assist you in finding a doctor who has agreed to participate in the act.”

California’s legislation, which was enacted on June 9, 2016, requires that patients must be at least 18 years old and mentally competent to make health care decisions — and that the lethal medication be self-administered. Two physicians must confirm a prognosis of six months or less to live, and a written and two oral requests must be made at least 15 days apart.​

But by the end of August, when Dale made contact with a willing Berkeley-based doctor who agreed to work with her, the clock started running over again on the statutorily mandated 15 day waiting period, the suit says, and it was too late for Dale.

Every day until her death on Sept. 13, according to the lawsuit, Dale repeatedly asked her daughters if it was the day she could obtain the aid in dying medication, but the 15-day waiting period had not yet expired.

“Her daughters had to tell their mother that she could not yet have the medication which would enable her to achieve a peaceful death as she wished,’’ the lawsuit says.

Dale died one day shy of the 15th day, “precisely the way she did not want to die, in bed, in a diaper, bleeding from her rectum and urinary tract, too confused by pain medications needed to manage the excruciating pain of terminal colorectal cancer to say goodbye,’’ the lawsuit says.

Filed on behalf of Dale’s two adult daughters by plaintiff’s attorneys Kathryn Stebner and Deena Zacharin,

the lawsuit alleges elder abuse and neglect; negligent infliction of emotional distress; misrepresentation/fraud and negligence.

It also demands a jury trial and seeks unspecified general, special and punitive damages.

Filed under: General Problems | 1 Comment »

Sudden, Unexpected Death in Chronic Pain Patients

https://www.practicalpainmanagement.com/sudden-unexpected-death-chronic-pain-patients

Severe pain, independent of medical therapy, may cause sudden, unexpected death. Cardiac arrest is the cause, and practitioners need to know how to spot a high-risk patient.

Sudden, unexpected death may occur in a severe, chronic pain patient, and the terminal event may be unrelated to medical therapeutics. Fortunately, sudden death is not as commonly observed in pain patients as in past years most likely due to better access to at least some treatment. Sudden death still occurs, however, and practitioners need to know how to spot an “at-risk” patient.

Unexpected, sudden death due to severe pain is poorly appreciated, since many observers still view severe pain as a harmless nuisance rather than a potential physiologic calamity. In many cases, just prior to death, the patient informs their family that they feel more ill than usual and seek relief in their bed or on their couch. Unfortunately, some of these patients don’t awaken. Other patients die, without warning, in their sleep or are found collapsed on the floor. Modern medicine’s aggressive toxicology and forensic procedures after death have contributed to the poor understanding of pain’s death threat. In some cases, a pain patient that was being treated appropriately with an opioid or other agent with overdose or abuse potential has suddenly and unexpectedly died. Drugs were found in body fluids after death, and in my opinion a coroner wrongly declared the death to be an “accidental overdose” or “toxic reaction” to drugs rather than implicate the real culprit, which may have been an “out-of-control” pain flare.

This article is partially intended to call attention to the fact that the mere finding of abusable drugs at autopsy doesn’t necessarily mean that the drugs caused the death. In fact, the drugs may have postponed death. Some physicians have been falsely accused of causing deaths due to drug overtreatment when, in fact, undertreatment of pain may have caused the death. Additionally, opioid blood levels assessed at autopsy of a patient who died suddenly are all too often wrongfully considered accidental overdoses because the pathologist is unaware that chronic pain patients on a stable dose of opioids can be fully functional with serum levels of their prescribed opioids that far exceed lethal levels in opioid-naïve patients.¹

Given here are the mechanisms of sudden, unexpected death in pain patients and some protective measures that practitioners must take to keep from being falsely accused of causing a sudden, unexpected death. More importantly, given here are some clinical tips to help identify the chronic pain patient who is at high risk of sudden, unexpected death so that more aggressive pain treatment can be rendered.

A Brief Anecdotal History
As a senior medical student at Kansas University in the early 1960s, I was required to take a rural preceptorship with a country doctor. In making our rounds one day to the county’s nursing home, I heard a farmer’s wife declare, “pain killed my mother last night.” Since then, I’ve repeatedly heard that pain killed a loved one. Folklore frequently mentions that people die “from,” as well as “in” pain. There is, however, little written detail of these events.

In the early years of my pain practice, which I began in 1975, I had several patients die suddenly and unexpectedly. This rarely happens to me today as I’ve learned to “expect the unexpected” and to identify which patients are at high risk of sudden death. In recent years, I’ve reviewed a number of litigation and malpractice cases of sudden, unexpected death in chronic pain patients. In some of these cases, physicians were accused of over- or misprescribing and causing a sudden, unexpected death, even though the patient had taken stabilized dosages of opioids and other drugs for extended periods. Also, the autopsy showed no evidence of pulmonary edema (a defining sign for overdose and respiratory depression). In cases where the physician was falsely accused, the post-death finding of abusable drugs in body fluids caused a family member, regulatory agency, or public attorney to falsely bring charges against a physician.

Setting and Cause
Unexpected deaths in chronic pain patients usually occur at home. Sometimes the death is in a hospital or detoxification center. The history of these patients is rather typical. Most are too ill to leave home and spend a lot of time in bed or on a couch. Death often occurs during sleep or when the patient gets up to go to the toilet. In some cases, the family reports the patient spent an extraordinary amount of time on the toilet just prior to collapse and death. Sudden and unexpected death, however, can occur anywhere at any time, as pain patients who have died unexpectedly and suddenly have been found at work or in a car.

Coronary spasm and/or cardiac arrhythmia leading to cardiac arrest or asystole is the apparent cause of death in the majority of these cases, since no consistent gross pathology has been found at autopsy.^2-5 Instant cardiac arrest appears to account for sudden collapse or death during sleep. Perhaps constipation and straining to pass stool may be cardiac strain factors as some pain patients die during defecation. Acute sepsis due to adrenal failure and immune suppression may account for some sudden deaths.

Two Mechanisms of Cardiac Death
Severe pain is a horrific stress.^6,7 Severe pain flares, acute or chronic, cause the hypothalamic-pituitary-adrenal axis to produce glucocorticoids (cortisol, pregnenolone) and catecholamines (adrenalin and noradrenalin) in an effort to biologically contain the stress.^8,9 Catecholamines have a direct, potent stimulation effect on the cardiovascular system and severe tachycardia and hypertension result.¹⁰ Pulse rates may commonly rise to more than 100 beats per minute and even rise to more than 130 beats per minute. Blood pressure may reach more than 200 mmHg systolic and more than 120 mmHg diastolic. In addition to adrenal catecholamine release, pain flares cause overactivity of the autonomic, sympathetic nervous system, which add additional stimulation to catecholamine-induced tachycardia and hypertension. Physical signs of autonomic, sympathetic overactivity, in addition to tachycardia and hypertension, may include mydriasis (dilated pupil), sweating, vasoconstriction with cold extremities, hyperreflexia, hyperthermia, nausea, diarrhea, and vomiting.

Filed under: General Problems | 2 Comments »

CVS/Caremark Complaints State of Florida Employee Plan 2015-2016

www.truthrx.org/2017/07/16/cvscaremark-complaints-state-florida-employee-plan-2015-2016/

Thanks to tax watch dog liberal public records laws in Florida, PUTT was able to obtain through the public records request process from the Department of Management Services the complaints from the state of Florida employees regarding their PBM – CVS/Caremark.  The request was specific for: 1 number of complaints and 2 nature of the complaints.

What was received were the “escalated” complaints with specific notes from the CSR (customer services representatives) who field the 800 number for CVS/Caremark.

The volume of requests (for 2015 and 2016) were overwhelming to say the least, so we’ve attempted to compile and condense the complaints in a document that will be forthcoming to our members, members of the media, plan sponsors, pharmacy association executives, pharmacy school professors and legislators.  If you are interested in the compilation, send us an email to info@truthrx.org.

2015 January CVS Complaint to Customer Care Escalation

2015 February CVS Complaint to Customer Care Escalation

2015 March CVS Complaint to Customer Care Escalation

2015 April CVS Complaint to Customer Care Escalation

2015 May CVS Complaint to Customer Care Escalation

2015 June CVS Complaint to Customer Care Escalation

2015 July CVS Complaint to Customer Care Escalation

2015 August CVS Complaint to Customer Care Escalation

2015 September CVS Complaint to Customer Care Escalation

2015 October CVS Complaint to Customer Care Escalation

2015 October CVS Complaint to Customer Care Escalation

2015 November CVS Complaint to Customer Care Escalation

2015 December CVS Complaint to Customer Care Escalation

2016 January CVS Complaint to Customer Care Escalation

2016 February CVS Complaint to Customer Care Escalation

2016 March CVS Complaint to Customer Care Escalation

2016 April CVS Complaint to Customer Care Escalation

2016 May CVS Complaint to Customer Care Escalation

2016 June CVS Complaint to Customer Care Escalation

2016 July CVS Complaint to Customer Care Escalation

2016 August CVS Complaint to Customer Care Escalation

2016 September CVS Complaint to Customer Care Escalation

2016 October CVS Complaint to Customer Care Escalation

2016 November CVS Complaint to Customer Care Escalation

2016 December CVS Complaint to Customer Care Escalation

Filed under: General Problems | Leave a Comment »